2019

• Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance. (Cell)

• West Nile Virus-Inclusive Single-Cell RNA Sequencing Reveals Heterogeneity in the Type 1 Interferon Responses within Single Cells. (J Virol)

2018

• Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication. (PLoS Pathog)

• Progestin-based contraception regimens modulate expression of putative HIV risk factors in the vaginal epithelium of pig-tailed Macaques. (Am J Reprod Immunol)

• Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. (Immunity)

• The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen. (Sci Transl Med)

• Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies. (Front Immunol)

• Short-term pIFN-α2a treatment does not significantly reduce the viral reservoir of SIV-infected, ART-treated rhesus macaques. (J Virol)

• Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors. (EBioMedicine)

• Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity. (Nat Commun)

• BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. (Genome Med)

• Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques. (J Virol)

• Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host. (Nature)

2017

• The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells. (Oncotarget)

• mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation. (Science)

• Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. (J Virol)

• The rectal mucosa and condomless receptive anal intercourse in HIV-negative MSM: implications for HIV transmission and prevention. (Mucosal Immunol)

• Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection. (PNAS)

2016

• Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae. (Nature Microbiol)

• Increased irritability, anxiety, and immune reactivity in transgenic Huntington's disease monkeys. (Brain Behav Immun)

• Coexpression Network Analysis of Benign and Malignant Phenotypes of SIV-Infected Sooty Mangabey and Rhesus Macaque. (PLos One)

• The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1. (AIDS Res Hum Retroviruses)

• Transcriptome Analysis of GVHD Reveals Aurora Kinase A as a Targetable Pathway for Disease Prevention. (Sci Transl Med)

• CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection. (Am J Transplant)

• Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood. (Proc Natl Acad Sci)

2015

• Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques. (J Clin Invest)

• Decreased TFR/TFH ratio in SIV-infected rhesus macaques may contribute to accumulation of TFH cells in chronic infection. (J Immunol)

• Cataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle of Pig-Tailed Macaques by Using a Systems Biology Approach. (J Virol)

• A GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiency. (Clin Transl Immunology)

• Type I interferon: understanding its role in HIV pathogenesis and therapy. (Curr HIV/AIDS Rep)

• Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. (Hepatology)

2014

• Nonpathogenic SIV Infection of Sooty Mangabeys (Encyclopedia of AIDS)

• A new rhesus macaque assembly and annotation for next-generation sequencing analyses. (Biol Direct)

• Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells Is Associated with Lack of Progression in Viremic Individuals. (PLos Pathog)

• Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. (Nature)

2013

• Intact type I Interferon production and IRF7 function in sooty mangabeys. (PLos Pathog)

• Transcriptional profiling of experimental CD8(+) lymphocyte depletion in rhesus macaques infected with simian immunodeficiency virus SIVmac239. (J Virol)

• Protection Afforded by an HIV Vaccine Candidate in Macaques Depends on the Dose of SIVmac251 at Challenge Exposure. (J Virol)

• Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques. (J Leuk Biol)

2012

• Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation. (Blood)

• PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. (J Clin Invest)

• CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T-cells in healthy, SIV-uninfected rhesus macaques. (J Med Primatol)

2011

• Primate genomes for biomedicine. (Nature Biotechnology)

• Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque. (J Clin Invest)

2009

• Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. (J Clin Invest)